BDBM19272 9-oxo-N-[(1R)-1-phenylethyl]-9,10-dihydroacridine-3-carboxamide::Acridone-Based Inhibitor, 8d

SMILES [H][C@](C)(NC(=O)c1ccc2c(c1)[nH]c1ccccc1c2=O)c1ccccc1

InChI Key InChIKey=BCOFSTGTSIOSBF-CQSZACIVSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 19272   

TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM19272(9-oxo-N-[(1R)-1-phenylethyl]-9,10-dihydroacridine-...)
Affinity DataIC50:  95nMpH: 8.0 T: 2°CAssay Description:Inhibition assays were performed using recombinant human IMPDH type 2 and varying concentrations of inhibitor. The production of NADH was monitored b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed