BDBM19285 2-fluoro-9-oxo-N-(2-{2H,3H,4H-pyrido[3,2-b][1,4]oxazin-7-yl}propan-2-yl)-9,10-dihydroacridine-3-carboxamide::Acridone-Based Inhibitor, 4i

SMILES CC(C)(NC(=O)c1cc2[nH]c3ccccc3c(=O)c2cc1F)c1cnc2NCCOc2c1

InChI Key InChIKey=SOGONSJMRDJQLC-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 19285   

TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM19285(2-fluoro-9-oxo-N-(2-{2H,3H,4H-pyrido[3,2-b][1,4]ox...)
Affinity DataIC50:  17nM EC50:  920nMpH: 8.0 T: 2°CAssay Description:Inhibition assays were performed using recombinant human IMPDH type 2 and varying concentrations of inhibitor. The production of NADH was monitored b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed