BDBM19293 (R)-N-(1-(5-(2-(1H-Indol-3-yl)ethyl)-4-benzyl-4H-1,2,4-triazol-3-yl)-2-(1H-indol-3-yl)ethyl)-2-amino-2-methylpropanamide::2-amino-N-[(1R)-1-{4-benzyl-5-[2-(1H-indol-3-yl)ethyl]-4H-1,2,4-triazol-3-yl}-2-(1H-indol-3-yl)ethyl]-2-methylpropanamide::CHEMBL374073::Trisubstituted 1,2,4-Triazole, 1

SMILES CC(C)(N)C(=O)N[C@H](Cc1c[nH]c2ccccc12)c1nnc(CCc2c[nH]c3ccccc23)n1Cc1ccccc1

InChI Key InChIKey=BLVAQCTVXRMXDP-GDLZYMKVSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 19293   

TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Cnrs

LigandPNGBDBM19293((R)-N-(1-(5-(2-(1H-Indol-3-yl)ethyl)-4-benzyl-4H-1...)
Affinity DataIC50:  15nM EC50:  64nMpH: 7.3 T: 2°CAssay Description:Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Cnrs

LigandPNGBDBM19293((R)-N-(1-(5-(2-(1H-Indol-3-yl)ethyl)-4-benzyl-4H-1...)
Affinity DataEC50:  64nMAssay Description:Agonist activity at human GHS1a receptor expressed in CHO cells assessed as induction of intracellular calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Cnrs

LigandPNGBDBM19293((R)-N-(1-(5-(2-(1H-Indol-3-yl)ethyl)-4-benzyl-4H-1...)
Affinity DataIC50:  15nMAssay Description:Displacement of [125I-His9]ghrelin from human GHS1a receptor expressed in LLC PK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed