BDBM19294 2-amino-N-[(1R)-2-(1H-indol-3-yl)-1-{5-[2-(1H-indol-3-yl)ethyl]-4-[(4-methoxyphenyl)methyl]-4H-1,2,4-triazol-3-yl}ethyl]-2-methylpropanamide::CHEMBL374643::Trisubstituted 1,2,4-Triazole, 2

SMILES COc1ccc(Cn2c(CCc3c[nH]c4ccccc34)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)C(C)(C)N)cc1

InChI Key InChIKey=RJPIWPXFPIJADI-SSEXGKCCSA-N

Data  5 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 19294   

TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM19294(2-amino-N-[(1R)-2-(1H-indol-3-yl)-1-{5-[2-(1H-indo...)
Affinity DataIC50:  6nMAssay Description:Displacement of [125I]His9-ghrelin from human GHSR1a receptor expressed in LLC PK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM19294(2-amino-N-[(1R)-2-(1H-indol-3-yl)-1-{5-[2-(1H-indo...)
Affinity DataIC50:  190nMAssay Description:Antagonist activity at human GHSR1a receptor expressed in CHO cells assessed as reduction of ghrelin-induced intracellular calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed