BDBM19296 2-amino-N-[(1R)-2-(1H-indol-3-yl)-1-{4-[(4-methoxyphenyl)methyl]-5-(2-phenylethyl)-4H-1,2,4-triazol-3-yl}ethyl]acetamide::JMV2959::Trisubstituted 1,2,4-Triazole, 4
SMILES COc1ccc(Cn2c(CCc3ccccc3)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)CN)cc1
InChI Key InChIKey=OZSZELOMMMKWTM-HHHXNRCGSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 19296
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Univ Montpellier
Curated by ChEMBL
Univ Montpellier
Curated by ChEMBL
Affinity DataKi: 43nMAssay Description:Displacement of red-ghrelin from SNAP-tagged human GHSR expressed in HEK293 cells incubated for 3 hrs at 4 degC or for 1 hr at room temperature by HT...More data for this Ligand-Target Pair
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Univ Montpellier
Curated by ChEMBL
Univ Montpellier
Curated by ChEMBL
Affinity DataIC50: 32nM Kd: 19nMpH: 7.3 T: 2°CAssay Description:Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co...More data for this Ligand-Target Pair
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Univ Montpellier
Curated by ChEMBL
Univ Montpellier
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Displacement of 125I-[His9]-ghrelin from human GHSR1a expressed in LLC-PK1 cells by competitive binding assayMore data for this Ligand-Target Pair