BDBM193019 US9193726, 7

SMILES Cc1cn(cn1)-c1ccc2C(=O)N(C[C@@H]3C[C@@H](F)[C@@H](O3)c3ccc(cc3)C(F)(F)F)CCn2c1=O

InChI Key InChIKey=HHALZMAKFSSPFQ-UEXGIBASSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 193019   

TargetPresenilin-1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM193019(US9193726, 7)
Affinity DataIC50:  73.5nMT: 2°CAssay Description:The ability of compounds to modulate production of amyloid beta protein Abeta(1-42) was determined using human WT-APP overexpressing CHO cells. Cel...More data for this Ligand-Target Pair
In DepthDetails US Patent