BDBM193020 US9193726, 8

SMILES C[C@@H]([C@@H]1CC[C@@H](O1)c1ccc(cc1)C(F)(F)F)N1CCn2c(ccc(-n3cnc(C)c3)c2=O)C1=O

InChI Key InChIKey=CZCJRJMKFMFGOG-WQTXXOFMSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 193020   

TargetPresenilin-1(Homo sapiens (Human))
Forum Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM193020(US9193726, 8)
Affinity DataEC50:  14nMAssay Description:Modulation of gamma-secretase in CHO cells expressing human APP assessed as reduction in amyloid beta (1 to 42 residues) production after 24 hrs by E...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Forum Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM193020(US9193726, 8)
Affinity DataIC50:  14.3nMT: 2°CAssay Description:The ability of compounds to modulate production of amyloid beta protein Abeta(1-42) was determined using human WT-APP overexpressing CHO cells. Cel...More data for this Ligand-Target Pair
In DepthDetails US Patent