BDBM193349 US9199927, 108::US9199927, 60

SMILES CC(C(=O)N(CC(O)=O)Cc1cccc(c1)C(O)=O)c1ccc(OC(=O)c2ccc(NC(N)=N)cc2)cc1Cl

InChI Key InChIKey=UCLUAJGIZROTHN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 193349   

TargetSerine protease 1(Homo sapiens (Human))
Astellas Pharma

US Patent
LigandPNGBDBM193349(US9199927, 108 | US9199927, 60)
Affinity DataIC50:  0.210nMpH: 8.0 T: 2°CAssay Description:The compound was dissolved in dimethyl sulfoxide (DMSO), and diluted to an arbitrary concentration (A). A was 100-fold diluted with a buffer (0.1 M T...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTrypsinogen 16(Mus musculus (Mouse))
Astellas Pharma

US Patent
LigandPNGBDBM193349(US9199927, 108 | US9199927, 60)
Affinity DataIC50:  0.140nMpH: 8.0 T: 2°CAssay Description:The compound was dissolved in dimethyl sulfoxide (DMSO), and diluted to an arbitrary concentration (A). A was 100-fold diluted with a buffer (0.1 M T...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTrypsinogen 16(Mus musculus (Mouse))
Astellas Pharma

US Patent
LigandPNGBDBM193349(US9199927, 108 | US9199927, 60)
Affinity DataIC50:  0.210nMpH: 8.0 T: 2°CAssay Description:The compound was dissolved in dimethyl sulfoxide (DMSO), and diluted to an arbitrary concentration (A). A was 100-fold diluted with a buffer (0.1 M T...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine protease 1(Homo sapiens (Human))
Astellas Pharma

US Patent
LigandPNGBDBM193349(US9199927, 108 | US9199927, 60)
Affinity DataIC50:  0.190nMpH: 8.0 T: 2°CAssay Description:The compound was dissolved in dimethyl sulfoxide (DMSO), and diluted to an arbitrary concentration (A). A was 100-fold diluted with a buffer (0.1 M T...More data for this Ligand-Target Pair
In DepthDetails US Patent