BDBM19385 2,4-diaminopyrimidine derivative, 8a::6-[(benzyloxy)methyl]-5-(4-{[(4-chlorophenyl)methyl]amino}phenyl)pyrimidine-2,4-diamine::JMC494459 4b

SMILES Nc1nc(N)c(c(COCc2ccccc2)n1)-c1ccc(NCc2ccc(Cl)cc2)cc1

InChI Key InChIKey=YHNPYJODGMGFSJ-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 19385   

TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM19385(2,4-diaminopyrimidine derivative, 8a | 6-[(benzylo...)
Affinity DataIC50:  19nM EC50:  180nMpH: 7.4 T: 2°CAssay Description:Specific binding was determined by incubation of membranes from GHS-R1a transfected CHO-K cells with 125I-His9-ghrelin in the presence of increasing ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM19385(2,4-diaminopyrimidine derivative, 8a | 6-[(benzylo...)
Affinity DataIC50:  300nMpH: 7.3 T: 2°CAssay Description:DHFR activity was determined by measuring the rate of depletion of NADPH, monitored at 340 nm, with a Beckman DU-7400 spectrophotometer. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed