BDBM194113 US9200001, 28
SMILES COc1ccc(Cc2nc(C)nn2-c2cc(nc(C)n2)C2CC2c2nc3ccccc3n2C)cc1OC
InChI Key InChIKey=RVKRYCLIKMXLEO-UHFFFAOYSA-N
Data 1 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 194113
TargetIsoform PDE10A2 of cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (PDE10A2)(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataKi: 0.00300nMAssay Description:In a typical experiment the PDE10 inhibitory activity of the compounds
of the present invention was determined in accordance with the following
exp...More data for this Ligand-Target Pair