BDBM194456 US9200016, 138::US9902710, Compound 138
SMILES COc1cc2cncc(Cc3cnc4ccc(OCC(N)=O)cc4c3)c2cc1OC
InChI Key InChIKey=XPXPQCNIPURPPX-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 194456
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Exonhit Therapeutics
US Patent
Exonhit Therapeutics
US Patent
Affinity DataIC50: 2.5nMAssay Description:The phosphodiesterase assay was developed using the LANCE® cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...More data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Exonhit Therapeutics
US Patent
Exonhit Therapeutics
US Patent
Affinity DataIC50: 2.5nMpH: 7.4 T: 2°CAssay Description:The phosphodiesterase assay was developed using the LANCE cAMP kit
(PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1%
BSA, and 1....More data for this Ligand-Target Pair