BDBM194487 US9200016, 169::US9902710, Compound 169
SMILES COCc1ncc(Cc2cnc3ccc(O)c(c3c2)C(F)(F)F)c2cc(OC)c(OC)cc12
InChI Key InChIKey=AQCSZBJZPWCJBX-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 194487
TargetIsoform 3 of cAMP-specific 3',5'-cyclic phosphodiesterase 4D (hPDE4D3)(Homo sapiens (Human))
Allergan
US Patent
Allergan
US Patent
Affinity DataIC50: 194nMpH: 7.4 T: 2°CAssay Description:The phosphodiesterase assay was developed using the LANCE cAMP kit
(PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1%
BSA, and 1....More data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Allergan
US Patent
Allergan
US Patent
Affinity DataIC50: 4.5nMpH: 7.4 T: 2°CAssay Description:The phosphodiesterase assay was developed using the LANCE cAMP kit
(PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1%
BSA, and 1....More data for this Ligand-Target Pair