BDBM194785 US9206167, 6::USRE48059, Compound of Example 6

SMILES Cc1cc2ccc(OCCCCN3CCN(CC3)c3cccc4sccc34)cc2[nH]c1=O

InChI Key InChIKey=PHLDMSHQFGMHOE-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 194785   

TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM194785(US9206167, 6 | USRE48059, Compound of Example 6)
Affinity DataKi:  0.800nMAssay Description:Dopamine D2: The binding assay was performed using 40 μl of the membrane specimen, 20 μl of [3H]-raclopride (final concentration 1 to 2 nM)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM194785(US9206167, 6 | USRE48059, Compound of Example 6)
Affinity DataKi:  0.800nM ΔG°:  -12.4kcal/molepH: 7.4 T: 2°CAssay Description:The assay was performed according to the method by Kohler et al. (Kohler C, Hall H, Ogren S O and Gawell L, Specific in vitro and in vivo binding of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent