BDBM1952 (Alkylamino)piperidine BHAP Analog 8::1-[[5-[(Methylsulfonyl)amino]indol-2-yl]carbonyl]-4-[N-methyl-N-[3-[(1,1-dimethylpropyl)amino]-2-pyridinyl]amino]piperidine::N-[2-({4-[methyl({3-[(2-methylbutan-2-yl)amino]pyridin-2-yl})amino]piperidin-1-yl}carbonyl)-1H-indol-5-yl]methanesulfonamide
SMILES CCC(C)(C)Nc1cccnc1N(C)C1CCN(CC1)C(=O)c1cc2cc(NS(C)(=O)=O)ccc2[nH]1
InChI Key InChIKey=RVKNVPBLJVAPAG-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 1952
Affinity DataIC50: 350nMpH: 8.3 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C](Human immunodeficiency virus type 1)
Upjohn
Upjohn
Affinity DataIC50: 530nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1027,P823L]/[588-1147,P823L](Human immunodeficiency virus type 1)
Upjohn
Upjohn
Affinity DataIC50: 3.33E+3nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair