BDBM195558 (2E)-2-(Pyridin-2-ylmethylidene)-2,3-dihydro-1H-inden-1-one (11c)

SMILES O=C1\C(Cc2ccccc12)=C\c1ccccn1

InChI Key InChIKey=SQKDIBYWOIDSOX-ZRDIBKRKSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 195558   

TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
North-West University

LigandPNGBDBM195558((2E)-2-(Pyridin-2-ylmethylidene)-2,3-dihydro-1H-in...)
Affinity DataIC50:  853nMpH: 7.4Assay Description:Recombinant human MAO-A and MAO-B were used for these studies and kynuramine served as enzyme substrate. Kynuramine is oxidised by both MAO isoform...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))TBA
LigandPNGBDBM195558((2E)-2-(Pyridin-2-ylmethylidene)-2,3-dihydro-1H-in...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human MAO-B using kynuramine as substrate incubated for 20 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))TBA
LigandPNGBDBM195558((2E)-2-(Pyridin-2-ylmethylidene)-2,3-dihydro-1H-in...)
Affinity DataIC50:  1.53E+3nMpH: 7.4Assay Description:Recombinant human MAO-A and MAO-B were used for these studies and kynuramine served as enzyme substrate. Kynuramine is oxidised by both MAO isoform...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed