BDBM195565 (2E)-2-(Thiophen-3-ylmethylidene)-2,3-dihydro-1H-inden-1- one (11k)

SMILES O=C1\C(Cc2ccccc12)=C\c1ccsc1

InChI Key InChIKey=TVLJTLQCDJYBBE-KPKJPENVSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 195565   

TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
North-West University

LigandPNGBDBM195565((2E)-2-(Thiophen-3-ylmethylidene)-2,3-dihydro-1H-i...)
Affinity DataIC50:  114nMpH: 7.4Assay Description:Recombinant human MAO-A and MAO-B were used for these studies and kynuramine served as enzyme substrate. Kynuramine is oxidised by both MAO isoform...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
North-West University

LigandPNGBDBM195565((2E)-2-(Thiophen-3-ylmethylidene)-2,3-dihydro-1H-i...)
Affinity DataIC50:  1.51E+3nMpH: 7.4Assay Description:Recombinant human MAO-A and MAO-B were used for these studies and kynuramine served as enzyme substrate. Kynuramine is oxidised by both MAO isoform...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed