BDBM195568 (2E)-5-Methoxy-2-[(5-methylfuran-2-yl)methylidene]-2,3-dihydro-1H-inden-1-one (11n)

SMILES COc1ccc2C(=O)\C(Cc2c1)=C\c1ccc(C)o1

InChI Key InChIKey=IEJAVDWNSNDMRX-FMIVXFBMSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 195568   

TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
North-West University

LigandPNGBDBM195568((2E)-5-Methoxy-2-[(5-methylfuran-2-yl)methylidene]...)
Affinity DataIC50:  4.73E+3nMpH: 7.4Assay Description:Recombinant human MAO-A and MAO-B were used for these studies and kynuramine served as enzyme substrate. Kynuramine is oxidised by both MAO isoform...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))TBA
LigandPNGBDBM195568((2E)-5-Methoxy-2-[(5-methylfuran-2-yl)methylidene]...)
Affinity DataIC50:  26nMAssay Description:Inhibition of human MAO-B using kynuramine as substrate incubated for 20 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))TBA
LigandPNGBDBM195568((2E)-5-Methoxy-2-[(5-methylfuran-2-yl)methylidene]...)
Affinity DataIC50:  26nMpH: 7.4Assay Description:Recombinant human MAO-A and MAO-B were used for these studies and kynuramine served as enzyme substrate. Kynuramine is oxidised by both MAO isoform...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed