BDBM19624 (2S)-2-[(7-chloro-1,3-benzoxazol-2-yl)amino]-3-cyclohexyl-N-[(2S)-1-[(3-methanesulfonylphenyl)amino]propan-2-yl]propanamide::Heterocyclic arylaminoethyl amide, 12c

SMILES C[C@@H](CNc1cccc(c1)S(C)(=O)=O)NC(=O)[C@H](CC1CCCCC1)Nc1nc2cccc(Cl)c2o1

InChI Key InChIKey=AIWUIXXWTABHNR-SBUREZEXSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 19624   

TargetCathepsin S(Homo sapiens (Human))
Gnf

LigandPNGBDBM19624((2S)-2-[(7-chloro-1,3-benzoxazol-2-yl)amino]-3-cyc...)
Affinity DataKi:  26nM ΔG°:  -10.8kcal/molepH: 5.5 T: 2°CAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Gnf

LigandPNGBDBM19624((2S)-2-[(7-chloro-1,3-benzoxazol-2-yl)amino]-3-cyc...)
Affinity DataKi:  199nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Gnf

LigandPNGBDBM19624((2S)-2-[(7-chloro-1,3-benzoxazol-2-yl)amino]-3-cyc...)
Affinity DataKi:  2.13E+3nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed