BDBM19630 (2S)-2-(1,3-benzoxazol-2-ylamino)-3-cyclohexyl-N-[(2S)-1-(5-fluoro-2,3-dihydro-1H-indol-1-yl)propan-2-yl]propanamide::Heterocyclic arylaminoethyl amide, 13b

SMILES C[C@@H](CN1CCc2cc(F)ccc12)NC(=O)[C@H](CC1CCCCC1)Nc1nc2ccccc2o1

InChI Key InChIKey=FLQPTDVBDVSSED-MBSDFSHPSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 19630   

TargetCathepsin S(Homo sapiens (Human))
Gnf

LigandPNGBDBM19630((2S)-2-(1,3-benzoxazol-2-ylamino)-3-cyclohexyl-N-[...)
Affinity DataKi:  26nM ΔG°:  -10.8kcal/molepH: 5.5 T: 2°CAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Gnf

LigandPNGBDBM19630((2S)-2-(1,3-benzoxazol-2-ylamino)-3-cyclohexyl-N-[...)
Affinity DataKi:  2.83E+3nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Gnf

LigandPNGBDBM19630((2S)-2-(1,3-benzoxazol-2-ylamino)-3-cyclohexyl-N-[...)
Affinity DataKi: >1.00E+4nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed