BDBM196476 US10202344, Compound 122::US9212139, 122
SMILES NC(=O)c1cccc2n(cc(C[C@H](O)CO)c12)-c1ccc(Oc2ccc(F)cc2)cc1
InChI Key InChIKey=WXUXQOGIRNAHNO-SFHVURJKSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 196476
Affinity DataKi: 300nMpH: 7.4Assay Description:For electrophysiological recordings the external solution was either standard, DMEM supplemented with 10 mM HEPES (pH adjusted to 7.34 with NaOH and ...More data for this Ligand-Target Pair
Affinity DataKi: 300nMAssay Description:Electrophysiology: On the day of experimentation, the 35 mm dish was placed on the stage of an inverted microscope equipped with a perfusion system t...More data for this Ligand-Target Pair
Affinity DataIC50: 222nMAssay Description:Recombinant Nav1.7 Cell Line: In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN...More data for this Ligand-Target Pair
Affinity DataIC50: 222nMpH: 7.3Assay Description:Assay Buffer: The assay buffer was formulated by removing 120 mL from a 1 L bottle of fresh, sterile dH2O (Mediatech, Herndon, Va.) and adding 100 mL...More data for this Ligand-Target Pair