BDBM19665 (2S)-N-[(2S)-3-methyl-1-{[4-(trifluoromethoxy)phenyl]amino}butan-2-yl]-4-(morpholin-4-yl)-4-oxo-2-phenylbutanamide::succinamide peptidomimetic, 31

SMILES CC(C)[C@@H](CNc1ccc(OC(F)(F)F)cc1)NC(=O)[C@@H](CC(=O)N1CCOCC1)c1ccccc1

InChI Key InChIKey=CNJNVNZFKGRALN-XZOQPEGZSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 19665   

TargetCathepsin S(Human)
Gnf

LigandPNGBDBM19665((2S)-N-[(2S)-3-methyl-1-{[4-(trifluoromethoxy)phen...)
Affinity DataKi:  25nM ΔG°:  -10.8kcal/molepH: 5.5 T: 37°CAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Human)
Gnf

LigandPNGBDBM19665((2S)-N-[(2S)-3-methyl-1-{[4-(trifluoromethoxy)phen...)
Affinity DataKi:  1.15E+4nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Human)
Gnf

LigandPNGBDBM19665((2S)-N-[(2S)-3-methyl-1-{[4-(trifluoromethoxy)phen...)
Affinity DataKi:  1.15E+4nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed