BDBM197676 US9216981, 4

SMILES Fc1ccc(NS(=O)(=O)c2cccs2)c(F)c1Nc1ncccc1-c1ncnc2[nH]cnc12

InChI Key InChIKey=AUPADWFQWOIWBW-UHFFFAOYSA-N

Data  4 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 197676   

TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Medpacto

US Patent
LigandPNGBDBM197676(US9216981, 4)
Affinity DataEC50:  30nMT: 2°CAssay Description:To check the B-Raf cell activity inhibitory capability of the compounds of the present invention, the following experiments were conducted in A375P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Medpacto

US Patent
LigandPNGBDBM197676(US9216981, 4)
Affinity DataEC50:  402nMAssay Description:Inhibition of wild type B-Raf in human MIAPaCa2 cells assessed as reduction in ERK phosphorylation preincubated for 1 hr by Western blot methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed