BDBM197676 US9216981, 4
SMILES Fc1ccc(NS(=O)(=O)c2cccs2)c(F)c1Nc1ncccc1-c1ncnc2[nH]cnc12
InChI Key InChIKey=AUPADWFQWOIWBW-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 197676
Affinity DataEC50: 30nMT: 2°CAssay Description:To check the B-Raf cell activity inhibitory capability of the compounds
of the present invention, the following experiments were conducted in
A375P...More data for this Ligand-Target Pair
Affinity DataEC50: 402nMAssay Description:Inhibition of wild type B-Raf in human MIAPaCa2 cells assessed as reduction in ERK phosphorylation preincubated for 1 hr by Western blot methodMore data for this Ligand-Target Pair