BDBM197686 US9216981, 14

SMILES Cc1c(Cl)cccc1S(=O)(=O)Nc1ccc(F)c(Nc2ncccc2-c2ncnc3[nH]cnc23)c1F

InChI Key InChIKey=XTFGLALDZROXLK-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 197686   

TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Medpacto

US Patent
LigandPNGBDBM197686(US9216981, 14)
Affinity DataEC50:  6nMT: 2°CAssay Description:To check the B-Raf cell activity inhibitory capability of the compounds of the present invention, the following experiments were conducted in A375P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Medpacto

US Patent
LigandPNGBDBM197686(US9216981, 14)
Affinity DataIC50:  2nMpH: 7.2 T: 2°CAssay Description:To check the B-Raf kinase inhibitory activity of the compounds of the present invention, the following experiments were conducted.(1) Serial Signalin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent