BDBM197689 US9216981, 17::US9550781, 24
SMILES Fc1ccc(NS(=O)(=O)c2ccsc2)c(F)c1Nc1ncccc1-c1ncnc2[nH]cnc12
InChI Key InChIKey=YSBVTNXKLLPITL-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 197689
Affinity DataIC50: 7nMpH: 7.2 T: 2°CAssay Description:To check the B-Raf kinase inhibitory activity of the compounds of the present invention, the following experiments were conducted.(1) Serial Signalin...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:In vitro B-RAF Kinase Assay. To determine iIn vitro activities of recombinant B-RAF enzyme, a Homogeneous Time-Resolved Fluorescence (HTRF) assay was...More data for this Ligand-Target Pair
Affinity DataEC50: 40nMT: 2°CAssay Description:To check the B-Raf cell activity inhibitory capability of the compounds
of the present invention, the following experiments were conducted in
A375P...More data for this Ligand-Target Pair