BDBM19810 CHEMBL118449::benzyl N-[(1S)-1-({1-[(2S)-2-{[(benzyloxy)carbonyl]amino}-4-methylpentanoyl]-3-oxopiperidin-4-yl}carbamoyl)-3-methylbutyl]carbamate::piperidinone analogue, 27
SMILES CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)NC1CCN(CC1=O)C(=O)[C@H](CC(C)C)NC(=O)OCc1ccccc1
InChI Key InChIKey=XGOULJOKRIZKRT-UWDVWBIHSA-N
Data 7 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 19810
Affinity DataKi: 2.60nM ΔG°: -11.6kcal/molepH: 5.5 T: 2°CAssay Description:Assays were carried out in the presence of variable concentrations of test compound. Reactions were initiated by addition of enzyme to buffered solut...More data for this Ligand-Target Pair
Affinity DataKi: 2.60nMAssay Description:Inhibition of cathepsin KMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Assays were carried out in the presence of variable concentrations of test compound. Reactions were initiated by addition of enzyme to buffered solut...More data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Inhibition of cathepsin LMore data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Assays were carried out in the presence of variable concentrations of test compound. Reactions were initiated by addition of enzyme to buffered solut...More data for this Ligand-Target Pair
Affinity DataKi: 440nMAssay Description:Inhibition of cathepsin BMore data for this Ligand-Target Pair
Affinity DataKi: 440nM ΔG°: -8.58kcal/molepH: 5.5 T: 2°CAssay Description:Assays were carried out in the presence of variable concentrations of test compound. Reactions were initiated by addition of enzyme to buffered solut...More data for this Ligand-Target Pair