BDBM19855 Balicatib::CHEMBL371064::N-[1-(cyanomethylcarbamoyl)cyclohexyl]-4-(4-propylpiperazin-1-yl)::N-{1-[(cyanomethyl)carbamoyl]cyclohexyl}-4-(4-propylpiperazin-1-yl)benzamide::basic piperazine-containing compound, 10

SMILES CCCN1CCN(CC1)c1ccc(cc1)C(=O)NC1(CCCCC1)C(=O)NCC#N

InChI Key InChIKey=LLCRBOWRJOUJAE-UHFFFAOYSA-N

Data  8 KI  15 IC50  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 19855   

TargetCathepsin S(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM19855(Balicatib | CHEMBL371064 | N-[1-(cyanomethylcarbam...)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of cathepsin S in human ramos cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM19855(Balicatib | CHEMBL371064 | N-[1-(cyanomethylcarbam...)
Affinity DataIC50:  48nMAssay Description:Inhibition of cathepsin L in human HepG2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Oryctolagus cuniculus (rabbit))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM19855(Balicatib | CHEMBL371064 | N-[1-(cyanomethylcarbam...)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of rabbit cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM19855(Balicatib | CHEMBL371064 | N-[1-(cyanomethylcarbam...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of human cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM19855(Balicatib | CHEMBL371064 | N-[1-(cyanomethylcarbam...)
Affinity DataIC50:  61nMAssay Description:Inhibition of cathepsin B in human HepG2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed