BDBM198911 US9221802, Ref. Ex. 76::US9315498, 76
SMILES CC1(C)CCN(C(=O)O1)c1ccc(cn1)C#Cc1cccc(F)c1
InChI Key InChIKey=FTNBPANQAKIJEL-UHFFFAOYSA-N
Data 2 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 198911
TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Homo sapiens (Human))
Hoffmann-La Roche
US Patent
Hoffmann-La Roche
US Patent
Affinity DataEC50: 13nMT: 2°CAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Homo sapiens (Human))
Hoffmann-La Roche
US Patent
Hoffmann-La Roche
US Patent
Affinity DataEC50: 13nMT: 2°CAssay Description:About 24 hrs before an experiment, 5x104 cells/well were seeded in
poly-D-lysine coated, black/clear-bottomed 96-well plates. The cells
were loaded...More data for this Ligand-Target Pair