BDBM199181 4-[(4-Carbamoylcyclohexyl)oxy]cyclohexane-1-carboxamide (OUL35)
SMILES NC(=O)c1ccc(Oc2ccc(cc2)C(N)=O)cc1
InChI Key InChIKey=XZRCQWLPMXFGHE-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 199181
TargetProtein mono-ADP-ribosyltransferase PARP11(Homo sapiens)
Oregon Health And Science University
Curated by ChEMBL
Oregon Health And Science University
Curated by ChEMBL
Affinity DataIC50: 2.09E+3nMAssay Description:Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...More data for this Ligand-Target Pair
TargetProtein mono-ADP-ribosyltransferase PARP10(Homo sapiens (Human))
Oregon Health And Science University
Curated by ChEMBL
Oregon Health And Science University
Curated by ChEMBL
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...More data for this Ligand-Target Pair
TargetProtein mono-ADP-ribosyltransferase PARP10(Homo sapiens (Human))
Oregon Health And Science University
Curated by ChEMBL
Oregon Health And Science University
Curated by ChEMBL
Affinity DataIC50: 1.32E+3nMAssay Description:Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...More data for this Ligand-Target Pair
TargetProtein mono-ADP-ribosyltransferase PARP11(Homo sapiens)
Oregon Health And Science University
Curated by ChEMBL
Oregon Health And Science University
Curated by ChEMBL
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...More data for this Ligand-Target Pair