BDBM199346 US9221831, 11
SMILES CO[C@]12CC[C@@]3(C[C@@H]1COc1ccc(cc1)-n1ccnc1)[C@H]1Cc4ccc(O)c5O[C@@H]2[C@]3(CCN1CC1CC1)c45
InChI Key InChIKey=CMCMYWCDPYASBI-UDCNLKFVSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 199346
Affinity DataKi: 0.0900nMpH: 7.4Assay Description:Radioligand dose displacement assays used 0.4 nM [3H]-U69,593 (GE Healthcare, Piscataway, N.J.; 40 Ci/mmole) with 15 μg membrane protein (recomb...More data for this Ligand-Target Pair
Affinity DataKi: 0.930nM ΔG°: -13.3kcal/molepH: 7.4 T: 2°CAssay Description:Radioligand dose-displacement binding assays for t-opioid receptors used 0.3 nM [3H]-diprenorphine (Perkin Elmer, Shelton, Conn.), with 5 mg membrane...More data for this Ligand-Target Pair
Affinity DataKi: 2.38nM ΔG°: -11.8kcal/molepH: 7.4 T: 2°CAssay Description:Delta-opioid Receptor Binding Assay Procedures were conducted as
follows. Radioligand dose-displacement assays used 0.3 nM
[3H]-Naltrindole (Perkin...More data for this Ligand-Target Pair
Affinity DataEC50: 6.06E+3nMpH: 7.4 T: 2°CAssay Description:Functional [35S]GTPgammaS binding assays were conducted as follows.
Delta opioid receptor membrane solution was prepared by sequentially
adding fin...More data for this Ligand-Target Pair