BDBM199418 US9221831, 84
SMILES CO[C@]12CC[C@@]3(C[C@@H]1COC(=O)[C@@H](N)Cc1ccccc1)[C@H]1Cc4ccc(O)c5O[C@@H]2[C@]3(CCN1CC1CC1)c45
InChI Key InChIKey=WANLIISAKAJTRU-LZDVKRKESA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 199418
Affinity DataKi: 0.0700nMpH: 7.4Assay Description:Radioligand dose displacement assays used 0.4 nM [3H]-U69,593 (GE Healthcare, Piscataway, N.J.; 40 Ci/mmole) with 15 μg membrane protein (recomb...More data for this Ligand-Target Pair
Affinity DataKi: 0.190nM ΔG°: -14.4kcal/molepH: 7.4 T: 2°CAssay Description:Radioligand dose-displacement binding assays for t-opioid receptors used 0.3 nM [3H]-diprenorphine (Perkin Elmer, Shelton, Conn.), with 5 mg membrane...More data for this Ligand-Target Pair
Affinity DataKi: 1.23nM ΔG°: -12.1kcal/molepH: 7.4 T: 2°CAssay Description:Delta-opioid Receptor Binding Assay Procedures were conducted as
follows. Radioligand dose-displacement assays used 0.3 nM
[3H]-Naltrindole (Perkin...More data for this Ligand-Target Pair
Affinity DataEC50: 2.04nMpH: 7.4 T: 2°CAssay Description:Functional [35S]GTPgammaS binding assays were conducted as follows. κ
opioid receptor membrane solution was prepared by sequentially adding
final ...More data for this Ligand-Target Pair
Affinity DataEC50: 0.820nMpH: 7.4 T: 2°CAssay Description:Functional [35S]GTPgammaS binding assays were conducted as follows.
Delta opioid receptor membrane solution was prepared by sequentially
adding fin...More data for this Ligand-Target Pair