BDBM19979 (2R,6S,7R)-12-hydroxy-7-(4-hydroxyphenyl)-8-oxatricyclo[7.4.0.0^{2,6}]trideca-1(9),10,12-trien-4-one::C-ring modified benzopyran scaffold, 2a

SMILES Oc1ccc(cc1)[C@@H]1Oc2ccc(O)cc2[C@@H]2CC(=O)C[C@H]12

InChI Key InChIKey=GUBQQMYDBCRCTJ-ZVZYQTTQSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 19979   

TargetEstrogen receptor beta(Homo sapiens (Human))
Eli Lilly

LigandPNGBDBM19979((2R,6S,7R)-12-hydroxy-7-(4-hydroxyphenyl)-8-oxatri...)
Affinity DataKi:  6.92nM ΔG°:  -11.0kcal/molepH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Eli Lilly

LigandPNGBDBM19979((2R,6S,7R)-12-hydroxy-7-(4-hydroxyphenyl)-8-oxatri...)
Affinity DataKi:  700nM ΔG°:  -8.31kcal/molepH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed