BDBM19993 CHEMBL62136::N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide::T 0901317::T0901317::TO-901317::US10543183, Compound TO901317::US10669296, Compound TO901317::US10945978, Compound 1::[3H]T0901317

SMILES OC(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1ccccc1)(C(F)(F)F)C(F)(F)F

InChI Key InChIKey=SGIWFELWJPNFDH-UHFFFAOYSA-N

Data  6 KI  62 IC50  2 Kd  107 EC50

PDB links: 9 PDB IDs match this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 19993   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM19993(CHEMBL62136 | N-[4-(1,1,1,3,3,3-hexafluoro-2-hydro...)
Affinity DataIC50:  810nMAssay Description:Inhibition of human GAL4-fused RORgammat LBD transfected in HEK293T cell measured after 24 hrs by by dual-glo luciferase assayMore data for this Ligand-Target Pair
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM19993(CHEMBL62136 | N-[4-(1,1,1,3,3,3-hexafluoro-2-hydro...)
Affinity DataIC50:  238nMAssay Description:Inhibition of human APC-labeled RORgammat LBD (262 to 518 residues) transfected in Escherichia coli BL21 (DE3) assessed as biotinylated SRC recruitme...More data for this Ligand-Target Pair