BDBM200220 2-(5-chloro-2-((2,4,6-tribromobenzyl)carbamoyl)phenoxy)acetic acid::MK184

SMILES OC(=O)COc1cc(Cl)ccc1C(=O)NCc1c(Br)cc(Br)cc1Br

InChI Key InChIKey=MOXQMGQGUBSXPN-UHFFFAOYSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 200220   

TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Institut De Ge??Ne??Tique Et De Biologie Mole??Culaire Et Cellulaire

LigandPNGBDBM200220(2-(5-chloro-2-((2,4,6-tribromobenzyl)carbamoyl)phe...)
Affinity DataIC50:  2.14E+4nMpH: 7.0Assay Description:The IC50-activity assays were carried out on the basis of the quantification of the NADPH consumption that takes place when the enzyme catalyzes the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B10 [K125R,V301L](Homo sapiens (Human))
Institut De Ge??Ne??Tique Et De Biologie Mole??Culaire Et Cellulaire

LigandPNGBDBM200220(2-(5-chloro-2-((2,4,6-tribromobenzyl)carbamoyl)phe...)
Affinity DataIC50:  1.00E+3nMpH: 7.0Assay Description:The IC50-activity assays were carried out on the basis of the quantification of the NADPH consumption that takes place when the enzyme catalyzes the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Institut De Ge??Ne??Tique Et De Biologie Mole??Culaire Et Cellulaire

LigandPNGBDBM200220(2-(5-chloro-2-((2,4,6-tribromobenzyl)carbamoyl)phe...)
Affinity DataIC50:  430nMpH: 7.0Assay Description:The IC50-activity assays were carried out on the basis of the quantification of the NADPH consumption that takes place when the enzyme catalyzes the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Institut De Ge??Ne??Tique Et De Biologie Mole??Culaire Et Cellulaire

LigandPNGBDBM200220(2-(5-chloro-2-((2,4,6-tribromobenzyl)carbamoyl)phe...)
Affinity DataIC50:  1.00E+3nMpH: 7.0Assay Description:The IC50-activity assays were carried out on the basis of the quantification of the NADPH consumption that takes place when the enzyme catalyzes the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB