BDBM200317 US9227956, 2
SMILES Clc1cccnc1N([C@@H]1CCCNC1)C(=O)c1ccc(cc1)-c1cnn2cccnc12
InChI Key InChIKey=TXOUQWKNVZZCNT-GOSISDBHSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 200317
Affinity DataIC50: 1.70E+3nMAssay Description:An in-vitro AlphaLISA assay (Perkin Elmer) was developed in order to quantitate the level of PCSK9 secreted into the cell culture media following com...More data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of human C-terminal V5 epitope tagged PCSK9 by luciferase reporter assayMore data for this Ligand-Target Pair
Affinity DataIC50: 690nMAssay Description:In order to eliminate the permeability barrier inherent to the WT7 and SCHH cell-based assays a cell-free system was also established to access compo...More data for this Ligand-Target Pair