BDBM200328 US9227956, 13
SMILES COC(=O)c1c(cnn1C)-c1ccc(cc1)C(=O)N([C@@H]1CCCNC1)c1ncccc1C
InChI Key InChIKey=VDRAMRAAPSBWGS-LJQANCHMSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 200328
Affinity DataIC50: 2.30E+3nMAssay Description:An in-vitro AlphaLISA assay (Perkin Elmer) was developed in order to quantitate the level of PCSK9 secreted into the cell culture media following com...More data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of PCSK9 translation in human THP-1 cells by AlphaLISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:In order to eliminate the permeability barrier inherent to the WT7 and SCHH cell-based assays a cell-free system was also established to access compo...More data for this Ligand-Target Pair