BDBM200342 US9227956, 26

SMILES Cn1ncc(c1-c1nn[nH]n1)-c1ccc(cc1)C(=O)N([C@@H]1CCCNC1)c1ncccc1Cl

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 200342   

TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM200342(US9227956, 26)
Affinity DataIC50:  5.75E+3nMAssay Description:In order to eliminate the permeability barrier inherent to the WT7 and SCHH cell-based assays a cell-free system was also established to access compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM200342(US9227956, 26)
Affinity DataIC50: >2.00E+4nMAssay Description:An in-vitro AlphaLISA assay (Perkin Elmer) was developed in order to quantitate the level of PCSK9 secreted into the cell culture media following com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent