BDBM200459 US9227969, 88

SMILES COc1cc(Oc2ncccn2)ccc1-c1cc2c3n([C@H]4CCN(C[C@@H]4F)C(=O)CO)c(C)nc3cnc2cc1F

InChI Key InChIKey=OSISKEFYDAAFSL-DHLKQENFSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 200459   

LigandPNGBDBM200459(US9227969, 88)
Affinity DataIC50:  5.70nMpH: 7.5Assay Description:A BRAF-MEK-ERK cascade assay is used to evaluate the effects of these compounds as inhibitors of the MAP kinase pathway. An enzymatic cascade assay i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent