BDBM20192 (1S,2R,5S,10S,11S,14R,15R)-2,15-dimethyl-14-[(2R)-6-methylheptan-2-yl]tetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-7-en-5-ol::cholesterol

SMILES [H][C@@]1(CC[C@@]2([H])[C@]3([H])CC=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)CCCC(C)C

InChI Key InChIKey=HVYWMOMLDIMFJA-DPAQBDIFSA-N

Data  5 IC50  6 Kd  2 EC50  1 Other

PDB links: 696 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 20192   

TargetOxysterol-binding protein 2(Homo sapiens (Human))
Dalhousie University

LigandPNGBDBM20192((1S,2R,5S,10S,11S,14R,15R)-2,15-dimethyl-14-[(2R)-...)
Affinity DataKd:  68nMpH: 7.4 T: 2°CAssay Description:Recombinant OSBP, ORP4L, or ORP4S (8 pmol) was incubated in 75 μl of binding buffer (10 mM HEPES (pH 7.4), 150 mM KCl, 2% (w/v) polyvinyl alcohol)...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterol-binding protein 2 [1-181,275-916](Homo sapiens (Human))
Dalhousie University

LigandPNGBDBM20192((1S,2R,5S,10S,11S,14R,15R)-2,15-dimethyl-14-[(2R)-...)
Affinity DataKd:  60nMpH: 7.4 T: 2°CAssay Description:Recombinant OSBP, ORP4L, or ORP4S (8 pmol) was incubated in 75 μl of binding buffer (10 mM HEPES (pH 7.4), 150 mM KCl, 2% (w/v) polyvinyl alcohol)...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed