BDBM202577 3-[4-(1,2-Dihydro-1,5-dimethyl-2-phenyl-3-oxo-3H-pyrazol-4-ylcarbonyl]isoxazole (16)

SMILES Cc1c(-c2nocc2SC#N)c(=O)n(-c2ccccc2)n1C

InChI Key InChIKey=SXGXGDGPVKCURF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 202577   

TargetAromatase(Homo sapiens (Human))TBA
LigandPNGBDBM202577(3-[4-(1,2-Dihydro-1,5-dimethyl-2-phenyl-3-oxo-3H-p...)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of recombinant human aromataseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAromatase(Homo sapiens (Human))TBA
LigandPNGBDBM202577(3-[4-(1,2-Dihydro-1,5-dimethyl-2-phenyl-3-oxo-3H-p...)
Affinity DataIC50:  2.30nMpH: 7.5 T: 2°CAssay Description:This fluorescence-based assay measures the rate at which recombinant human aromatase (baculovirus/insect cell-expressed) converts the substrate 7-m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed