BDBM203378 US9242981, 123

SMILES COc1cccc(F)c1CN1CC(CC(C1)C(F)(F)F)NC(=O)N1CCc2[nH]nc(c2C1)-c1ccnc(C)c1

InChI Key

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 203378   

TargetMitogen-activated protein kinase 1(Mus musculus (Mouse))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM203378(US9242981, 123)
Affinity DataIC50:  4.30nMAssay Description:Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was added to 14 &#...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 1(Mus musculus (Mouse))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM203378(US9242981, 123)
Affinity DataKd:  0.0600nMT: 2°CAssay Description:The SAR (Structure Activity Relationship) for ERK ligands covered by this invention was interrogated using the TdF (Temperature Dependence Fluoresc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent