BDBM20345 3-{[4-(azepan-1-yl)phenyl]methyl}-1-(3-methylisoquinolin-5-yl)urea::Isoquinoline Analogue, 39

SMILES Cc1cc2c(NC(=O)NCc3ccc(cc3)N3CCCCCC3)cccc2cn1

InChI Key InChIKey=CRXMYQXPWMGLMV-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 20345   

TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM20345(3-{[4-(azepan-1-yl)phenyl]methyl}-1-(3-methylisoqu...)
Affinity DataEC50:  3.80nMpH: 7.4 T: 2°CAssay Description:The functional antagonist activity of compounds at the TRPV1 receptor was determined with a Ca2+ influx assay by measuring the effect on capsaicin (0...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed