BDBM204998 I-29
SMILES COC[C@H]1OC(N)=N[C@@](C)([C@H]1F)c1cc(NC(=O)c2ccc(cn2)C#N)ccc1F
InChI Key InChIKey=RTRLKXJUOZLFHE-FUHIMQAGSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 204998
Affinity DataIC50: 26nMAssay Description:Inhibition of recombinant human BACE1 (43 to 454 residues) expressed in Escherichia coli BL21(DE3) using Biotin-epsilon-amino-n-capronic acid-SEVNLDA...More data for this Ligand-Target Pair
Affinity DataIC50: 25.8nMpH: 5.0 T: 2°CAssay Description:48.5 μL of substrate peptide solution (Biotin-XSEVNLDAEFRHDSGC-Eu: X=ε-amino-n-capronic acid, Eu=Europium cryptate) was added to each well...More data for this Ligand-Target Pair