BDBM205104 2-{[(3r,6r)-1-{[2-methoxy-6- (2h-1,2,3-triazol-2- yl)phenyl]carbonyl}-6- methylpiperidin-3-yl]oxy}-3- methylpyridine-4-carbonitrile::US9546152, example 14

SMILES COc1cccc(c1C(=O)N1C[C@@H](CC[C@H]1C)Oc1nccc(C#N)c1C)-n1nccn1

InChI Key InChIKey=XSLIXPOJDOPWIK-CRAIPNDOSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 205104   

TargetOrexin receptor type 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM205104(2-{[(3r,6r)-1-{[2-methoxy-6- (2h-1,2,3-triazol-2- ...)
Affinity DataIC50:  15nMAssay Description:The utility of the compounds in accordance with the present invention as orexin receptor OX1R and/or OX2R antagonists may be readily determined witho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM205104(2-{[(3r,6r)-1-{[2-methoxy-6- (2h-1,2,3-triazol-2- ...)
Affinity DataIC50:  507nMAssay Description:The utility of the compounds in accordance with the present invention as orexin receptor OX1R and/or OX2R antagonists may be readily determined witho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent