BDBM206032 1-(4-(4-((4-(5-((1R,3R)-2-(2,2- difluoroethyl)-3-methyl-2,3,4,9- tetrahydro-1H-pyrido[3,4-b]indol- 1-yl)pyrimidin-2-yl)piperazin-1- yl)methyl)piperidin-1- yl)phenyl)dihydropyrimidine- 2,4(1H,3H)-dione::US20260007681, Compound A38

SMILES C[C@@H]1Cc2c([nH]c3ccccc23)[C@@H](c2cnc(N3CCN(CC4CCN(c5ccc(N6CCC(=O)NC6=O)cc5)CC4)CC3)nc2)N1CC(F)F

InChI Key InChIKey=RABAFWIHYJUOOX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 206032   

TargetDNA damage-binding protein 1/Protein cereblon(Human)
University Of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 206032BDBM206032(1-(4-(4-((4-(5-((1R,3R)-2-(2,2- difluoroethyl)-3-m...)
Affinity DataIC50: 2.75E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2026
Entry Details
US Patent