BDBM208180 US9265773, 124::US9265773, 126

SMILES CNC(=O)c1c(oc2cc(N(C)S(C)(=O)=O)c(cc12)-c1ccc2OC(CNC(=O)[C@@H]3CCCN3C(=O)OC)n3c(cc4c(F)cccc34)-c2n1)-c1ccc(F)cc1

InChI Key InChIKey=WUDDLZILRXBAHO-MIXNXMPVSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 208180   

TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM208180(US9265773, 124 | US9265773, 126)
Affinity DataIC50:  19nMAssay Description:Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM208180(US9265773, 124 | US9265773, 126)
Affinity DataIC50:  1.40nMAssay Description:Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM208180(US9265773, 124 | US9265773, 126)
Affinity DataIC50:  4.5nMAssay Description:Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM208180(US9265773, 124 | US9265773, 126)
Affinity DataIC50:  2.70nMAssay Description:Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent