BDBM208771 US9266876, 238
SMILES C[C@@H]1CN(CCN1C(=O)Cn1nc(C)nc1C)c1sc(nc1-c1nc2ccc(cc2[nH]1)C1CCOCC1)C(F)(F)F
InChI Key InChIKey=VJHWXFTZYDAOIA-OAHLLOKOSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 208771
TargetC-X-C chemokine receptor type 3/Guanine nucleotide-binding protein subunit alpha-15(Homo sapiens (Human))
Actelion Pharmaceuticals
US Patent
Actelion Pharmaceuticals
US Patent
Affinity DataIC50: 1nMpH: 7.4 T: 2°CAssay Description:The bioactivity of compounds is tested in a fluorometric imaging plate reader (FLIPR: Molecular Devices) using engineered CHO-K1 cells expressing the...More data for this Ligand-Target Pair
Affinity DataIC50: 123nMAssay Description:Antagonist activity at human recombinant CXCR3 in human venous blood assessed as receptor internalization measured for 30 mins in presence of CXCL10 ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.30nMAssay Description:Antagonist activity at human recombinant CXCR3 expressed in CHO-K1 cells measured after 10 mins in presence of CXCL10 by FLIPR analysisMore data for this Ligand-Target Pair