BDBM208963 US9266881, 10-4
SMILES O=c1n(CCc2ccc3ncccc3n2)nc2c(cccn12)-c1ccncc1
InChI Key InChIKey=VRUXRYNFEDNSPK-UHFFFAOYSA-N
Data 1 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 208963
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataKi: 103nM ΔG°: -9.53kcal/molepH: 7.2 T: 2°CAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAPĀ® FP kit supplied by Molecular Devices, Sunn...More data for this Ligand-Target Pair