BDBM208969 US9266881, A-6
SMILES O=c1n(CCc2ccc3ccccc3n2)nc2cccc(N3CCCCC3)n12
InChI Key InChIKey=ARRXPXQIIIRWCT-UHFFFAOYSA-N
Data 1 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 208969
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataKi: 19nM ΔG°: -10.5kcal/molepH: 7.2 T: 2°CAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAPĀ® FP kit supplied by Molecular Devices, Sunn...More data for this Ligand-Target Pair