BDBM20922 Isoxazole, 41k::N-ethyl-5-[5-(4-fluorophenyl)-2,4-dihydroxyphenyl]-4-[4-(piperidin-1-ylmethyl)phenyl]-1,2-oxazole-3-carboxamide

SMILES CCNC(=O)c1noc(c1-c1ccc(CN2CCCCC2)cc1)-c1cc(c(O)cc1O)-c1ccc(F)cc1

InChI Key InChIKey=CDCLIURFWZMJLI-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 20922   

TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Vernalis (R&D)

LigandPNGBDBM20922(Isoxazole, 41k | N-ethyl-5-[5-(4-fluorophenyl)-2,4...)
Affinity DataIC50:  36nM EC50:  35nMAssay Description:The assay is based upon displacement of a fluorescently labeled molecule, which binds specifically to the ATP-binding site of full-length human Hsp90...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed