BDBM209866 PF-06651600::US11111242, Example 5::US20230348487, Example PF-06651600::US9617258, Example 5

SMILES C[C@H]1CC[C@H](CN1C(=O)C=C)Nc1ncnc2[nH]ccc12

InChI Key

Data  14 KI  71 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 209866   

TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Jinan University

Curated by ChEMBL
LigandPNGBDBM209866(PF-06651600 | US11111242, Example 5 | US2023034848...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of GST-tagged recombinant human JAK1 (866 to 1154 residues) expressed in baculovirus infection system by FRET assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Jinan University

Curated by ChEMBL
LigandPNGBDBM209866(PF-06651600 | US11111242, Example 5 | US2023034848...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of GST tagged recombinant human JAK2 expressed in baculovirus infection system by FRET assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Jinan University

Curated by ChEMBL
LigandPNGBDBM209866(PF-06651600 | US11111242, Example 5 | US2023034848...)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of GST tagged recombinant human JAK3 expressed in baculovirus infection system by FRET assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Jinan University

Curated by ChEMBL
LigandPNGBDBM209866(PF-06651600 | US11111242, Example 5 | US2023034848...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human TYK2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails PubMed